Liver Fibrosis Treatment in India

Liver fibrosis occurs when the healthy tissue of your liver becomes scarred and cannot work as well. Fibrosis is the first stage of liver scarring. Some fibrosis can be reversible.
Scarring of the liver occurs on a spectrum, with different degrees. Some of them may be treatable and reversible. However, medications and lifestyle changes can help to keep fibrosis from getting worse.

What are the causes of liver fibrosis?

Liver fibrosis occurs after a person experiences injury or inflammation in the liver. The liver’s cells stimulate wound healing. During this wound healing, excess proteins such as collagen and glycoproteins build up in the liver.
Eventually, after many instances of repair, the liver cells (known as hepatocytes) can no longer repair themselves. The excess proteins form scar tissue or fibrosis.

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What are the stages of liver fibrosis?

There are several different scales of liver fibrosis staging, where a doctor determines the degree of liver damage. This may be achieved with a variety of methods, such as blood work, imaging tests, and a tissue biopsy that may be further examined under a microscope (histology).
But a doctor will need to diagnose any underlying chronic liver disease, such as fatty liver disease or hepatitis. This can help identify the underlying causes of inflammation that lead to fibrosis, and better guide the staging and treatment process.
While fibrosis staging can help you and a doctor understand the degree to which your liver might be damaged, it’s important to note that identifying the underlying cause is more important than focusing on any particular stage.
If a liver biopsy and histology is performed, a doctor may stage liver fibrosis based on the METAVIR scoring system.
This assigns a “score” based on two factors: inflammation (activity) and damage (fibrosis). A lower score may indicate less inflammation and damage, while a higher score could mean more.

The activity grades range from A0 to A3:

A0: no activity
A1: mild activity
A2: moderate activity
A3: severe activity

The fibrosis stages range from F0 to F4:

F0: no fibrosis
F1: portal fibrosis without septa
F2: portal fibrosis with few septa
F3: numerous septa without cirrhosis
F4: cirrhosis

Therefore, a person with the most severe disease form may have an A3, F4 METAVIR score.
Another scoring system based in histology is Batts and Ludwig, which grades fibrosis on a scale of grade 1 to grade 4, with grade 4 being the most severe.
The International Association of the Study of the Liver (IASL) also has a histological scoring system with four categories that include:

Minimal chronic hepatitis
Mild chronic hepatitis
Moderate chronic hepatitis
Severe chronic hepatitis

Fibrosis staging may also be based on other tests outside of a liver biopsy and histology. For example, a doctor may confirm liver fibrosis with a blood test that measures fibrosis 4 (Fib4) in the blood.
could mean you’re at a high risk for liver fibrosis.
Additionally, fibrosis staging may be confirmed with the help of imaging tests. These look at the size and shape of your liver, as well as for excess fat, lumps, or shrinkage. Possible imaging study techniques include:

abdominal ultrasound
computed tomography (CT) scan of your abdomen
magnetic resonance imaging (MRI) scan
elastography, which is combined with either an ultrasound or MRI scan

Treatment:

Treatment options for liver fibrosis usually depend upon the underlying cause of the fibrosis. A doctor will treat the underlying illness, if possible, to reduce the effects of liver disease.
For example, if a person drinks alcohol excessively, a doctor may recommend a treatment program to help them stop drinking. If a person has NAFLD, a doctor may recommend making dietary changes to lose weight and taking medications to promote better blood sugar control.
Exercising and losing weight may also help to reduce the disease’s progression.

Treatments for specific causes of liver fibrosis include:

chronic liver disease:ACE inhibitors such as benazepril Lisinopril and ramipril
hepatitis C virus: direct action antivirals such as Epclusa, Harvoni, Mayvret, etc.
nonalcoholic steatohepatitis: PPAR-alpha agonist
autoimmune hepatitis: immunosuppressive therapy
alcohol liver disease: abstinence from alcohol

A doctor may also recommend antifibrotics that may possibly help reduce the likelihood of permanent liver scarring (cirrhosis). Depending on the drug, antifibrotics are classified as:

anti-inflammatories: examples include bela pectin, cenicriviroc, and liraglutide
hepatocyte apoptosis inhibitors: these include emricasan, pentoxifylline, and selonsertib
oxidative stress inhibitors: possibilities include methyl ferulic acid and losartan
hepatic stellate cell (HSC) inhibitors: these drugs target various cytokines that may activate HSCs
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and contribute to fibrosis

Still, there are limitations to antifibrotic treatment. While some of the above medications are used for other purposes, such as high blood pressure and vascular diseases, not all are yet approved for the treatment of liver fibrosis. Animal studies show promise, but human clinical trials are limited.
If a person’s liver fibrosis advances to where their liver is very scared and doesn’t work, a person’s only definitive treatment is often to receive a liver transplant. However, the waiting list is long for these transplant types and not every person is a surgical candidate.

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Max Hospital Saket

Number of beds: 500
ICU Beds: 267
Airport Distance: 13 KM

Brief About:

Max Super Speciality Hospital at Saket is one of the topmost healthcare service
Providers in India. The multi-super speciality hospital has a capacity of over 500 beds, 250 functional beds. It is equipped with state-of-the-art facilities, advanced technologies.
With the help of over 300 leading specialist Doctors, strong nursing staff, and state-of-the-art innovative medical tools.

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Max Hospital, Saket aims to provide the highest standard of medical care to the patients, right from admission and all the way to the patient discharge.
Max Smart Super Speciality Hospital, Saket, offers the advantage of integrated medical care in a multidisciplinary setting provided by a faculty of highly qualiﬁed doctors, nurses, & healthcare professionals.
Max Smart Super Speciality Hospital, Saket, is a regional hub for complex procedures such as neurovascular intervention, targeted cancer treatments, heart surgeries, orthopaedic surgeries, liver & kidney transplant, and fertility treatments.
With over 35 Speciality units, this renowned hospital caters to many patients from different parts of India as well as abroad on an everyday basis.
The super specialty hospital is well known for having Asia’s first and the world’s third BrainSUITE technology.
It is an advanced Neurosurgical operation theatre, which allows the medical team to use MRI during the surgery. This sophisticated technology can be used for various kinds of brain surgery.
Max Hospital group is also the first super speciality tertiary care centre that has the facility for advanced cardiac life support ambulances and air evacuation service.

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Fortis Memorial Research Institute

Number of beds:   1000
ICU Beds:     298
Airport Distance:  17 KMs

Brief About:

Fortis Memorial Research Institute was established in 2001.
It is an outstanding multi-speciality quaternary care hospital,having the top-notch infrastructure, advanced equipment, highly qualified and experienced medical professionals and super sub-specialists.
Fortis Hosptial Gurgaon is an advanced centre of excellence in Robotic Surgery, Neurosciences, Oncology, Renal Sciences, BMT, Organ Transplants, Orthopaedics, Cardiac Sciences and Obstetrics & Gynaecology.

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JCI & NABH Accredited Hospital, NABL Accredited Lab, NABH Certified Nursing Excellence, NABH Accredited Blood Bank
FMRI is a 1000 bedded and 15 Operation theaters and over 400 diagnostics centres (including JVs).
Medical facility endowed with a dedicated team of 200 world-renowned doctors, covering a number of specialities, who aim to provide the best quality medical care to all the patients, national as well as international.
This hospital is well set up with the latest technologies and equipment throughout all the specialties and research labs, which are accredited by NABL.
This ensures that the patients at FMRI receive diagnostic results and treatment with high accuracy and in minimum time.
With a vision for the community, FMRI operates various speciality clinics such as, for Paediatrics, Nephrology, Neurology, Gynecology, Orthopedics, Oncology and many more, which provide long term healthcare management and follow up care.
FMRI is the premium healthcare provider and endeavours to be known as the “Mecca of Medicine” – the ultimate healthcare destination.

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Artemis Hospital Gurgaon

Number of beds: 600
ICU Beds: 185
Airport Distance: 19 Km

Brief About:

Artemis Hospital, established in 2007, spread across 9 acres, is a 600plus bed; state-of-the-art multi-speciality hospital located in Gurgaon, India.
Artemis Hospital is the first JCI and NABH accredited hospital in Gurgaon.
Designed as one of the most advanced hospitals in India, Artemis provides a depth of expertise in the spectrum of advanced medical & surgical interventions, a comprehensive mix of inpatient and outpatient services.

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Artemis has around 400 + best doctors. It has put modern technology in the hands of renowned doctors from across the country and abroad to set new standards in healthcare.
The medical practices and procedures followed in the hospital are research-oriented and benchmarked against the best in the world.
Top-notch services, in a warm, open patient-centric environment, clubbed with affordability, has made us one of the most revered hospitals in the country.
Most Promising Start-Up of the Year 2007 award – Express Healthcare magazine
Best IT Implementation for the Year 2008 – PC Quest magazine for Hospital Information System
Best institute for Medical Value Year 2010 – The CNBC Awaaz travel awards
Asia Pacific Hand hygiene excellence Award Year 2011 – World Health Organisation (WHO)
The patient base is 400000
750000 surgeries conducted since the inception

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Manipal Hospital Dwarka

Number of beds: 380
ICU Beds: 118
Airport Distance: 8 Km

About Hospital:

Manipal Hospital Dwarka is a prominent multi-speciality and quaternary care providing hospital with first-rate healthcare services and integrated facilities.
The world-class medical centre is a part of Manipal Education and Medical Group (MEMG), one of India’s forerunner healthcare groups.
The group started with one flagship hospital in 1991 and now has bloomed into a network of 15 hospitals with a significant presence in Malaysia.

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The hospital offers a wide range of medical facilities at an affordable range, with the prime focus on the delivery of trusted and reliable therapeutic services to domestic as well as international patients.
The 380 bedded healthcare centre has state-of-the-art infrastructure, cutting edge technology and global standards in terms of clinical excellence.
It is one of the top hospitals in Delhi to offer impeccable medical services and is equipped with the latest diagnostic and curative technological advancements that are today available in the field of medicine.
Manipal Hospital is one of the most preferred destinations for medical travel and receives
a large number of international patients from all over the world, including the Middle East, Africa, and South-East Asia.
The hospital is fully committed to its goal to become a ‘Digital Hospital’, that has paperless services and seamless integration to its core.
The panel of renowned doctors at Manipal Hospital Dwarka are highly trained experts with years of experience in their field of expertise.

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Indraprastha Apollo Hospital

No. of beds: 900
ICU Beds: 262
Airport: 20kms

About Hospital:

Indraprastha Apollo Hospital is a flagship hospital of India’s foremost healthcare groups,the Apollo Group. It is a highly renowned multi-speciality facility that offers tertiary and quaternary care services to domestic and international patients.
The 900 bedded hospital is outfitted with the most modern technology for diagnostics as well as therapeutic purposes.
A team of highly trained medical professionals work under all the 52 specialities at the hospital.

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Indraprastha Apollo is an accredited hospital with international standard quality services for patient care and safety norms.
The hospital uses its own system, called The Apollo Standards of Clinical Care (TASCC), to maintain top standards for all kinds of treatment and procedures.
The Apollo Organ Transplant Program is one of the most successful programs in the country that has performed over 1627 transplants (410 Liver and 1210 Kidney), including 979 transplants (289 Liver and 690 Kidney) performed at the Transplant Program in Delhi.
It is the First Hospital in India to perform a Paediatric Liver Transplant in 1998. They have successfully performed various kinds of liver transplant for different kinds of liver conditions.
Indraprastha Apollo Hospital has some world-reputed surgeons and specialists who are the pioneers of their specialities, especially in Cardiology and Neurology.
The hospital has won many national and international accolades and continues to be one of the top healthcare service providers in India.
It is the first hospital in India to get international accreditation by international (JCI) consecutively for the fourth time

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Medanta-Hospital-Gurgaon

Medanta The Medicity Hospital

Number of beds: 1250
ICU Beds: 300
Airport Distance: 18 KMs

Brief About:

Medanta – The Medicity is amongst India’s largest and most renowned multi-super speciality healthcare centre with 1250 beds, 29 super speciality units and more than 800 accomplished doctors.
Supported by state-of-art infrastructure, all the departments in the hospital are fully equipped with cutting-edge technology, modular Operation Theatre and modernized monitoring systems in ICUs.
The panel of doctors from Medanta, headed by A.S.Soin performed the first successful intestinal transplant in India.

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The team of Medanta has performed over 15,000 cardiac surgeries and 2500 joint replacement surgeries.
It Has performed over 500 living donor liver transplants. It is the highest number of liver transplants done in India and the 2nd highest in the world.
Further to its credits, the doctors at Medanta are highly trained experts with international repute and have contributed in making world records and claimed many firsts not only in India but on a global scale.
It has all kinds of procedures like Liver transplant, intestine,transplant and Knee Replacement surgery.
The hospital maintains a high standard of quality clinical care and is operational with the latest technologies like 256 Slice CT, Brain Suite with Intraoperative MRI Imaging, Da Vinci a surgical system with Robot for Minimally Invasive Surgery, Artis- Zeego Endovascular Surgical Cath Lab- with combined operating room.

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Providing a doctor’s opinion and proper quotation
Selecting the best hospital and doctor as per your case
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Providing full guidance how to get Visa from your country
Providing total cost including treatment, air tickets, accommodation, and food
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BLK-Max Hospital

Number of beds: 700
ICU Beds: 175
Airport Distance: 13 Km

Brief About:

BLK Super Speciality Hospital was established by Dr. B.L. Kapur in 1959. It was inaugurated by the then Prime Minister of India, Pandit Jawahar Lal Nehru.
BLK Super Speciality Hospital was established by Dr. B.L. Kapur in 1959. It was inaugurated by the then Prime Minister of India, Pandit Jawahar Lal Nehru.
BLK has a unique combination of the best in class technology, put to use by the best names in the professional circles to ensure world-class health care to all patients.

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Spread on five acres of land, with a capacity of 700 beds,
BLK Super Speciality Hospital is one of the largest tertiary care private hospitals in the country,
BLK has consistently ranked amongst the Top 10 Multi Super Specialty Hospitals in Delhi NCR.
The outpatient services are spread on two floors with 80 consultation rooms. All ambulatory services have been designed with the intent to create dedicated aides for all specialities, with their interventional services in close vicinity.
The hospital has 17 state-of-the-art well equipped modular operation theatres with three-stage air filtration and gas scavenging system to ensure patient safety. All the Operation Theatres are fitted with best in class pendants, operating lights, anaesthesia workstations and advanced information management system.
The Hospital has one of the biggest critical care programmes in the region with 125 beds in different intensive care units viz Medical, Surgical, Cardiac, Paediatrics, Neonatology, Neurosciences and Organ Transplant.
Each Critical care unit is equipped with high-end patient monitoring devices, ventilators and dedicated isolation rooms.
Liver and Renal Transplant Centres have been equipped with dedicated ICUs with individual HEPA filters, specialized instruments and equipment.
Awarded the Prestigious Gold Award at Hospital Management Asia (HMA), Bangkok (2013) and HMA Awards 2014.

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Dr. Rela Institute and Medical Centre

Number of beds: 450
ICU Beds: 130
Airport Distance: 8 KMs

About Hospital:

Dr. Rela Institute & Medical Centre was established under the leadership of Prof. Mohamed Rela, a world-renowned surgeon in the field of Liver Surgery and Transplantation.
Dr. Rela made a world-record by performing a Liver Transplantation on a 5-day old baby and made his name in the Guinness Book of Records.
Dr. Mohamed Rela, who has performed more than 4000 liver transplant surgeries.

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Dr. Rela Institute & Medical Centre is a multi-super specialty hospital.
The hospital is committed to being an internationally significant health care system with the state-of-the art infrastructure facilities.
Dr. Rela Institute & Medical Centre houses one of the world’s largest dedicated liver intensive care units.
Dr. Rela Institute & Medical Centre is led and managed by world-renowned doctors who are committed to healthcare.
Hospital has trained team of staff and nurses, who are available 24*7 hours for patients.

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Manipal Hospital Bangalore

Number of beds: 600
ICU Beds: 124
Airport Distance: 18 KMs

About Hospital:

Established in the year 1991. Manipal Hospital HAL Airport Road is a multi-specialty hospital.
The hospital has 600 in-patient beds. The NABH and NABL accredited facility is among the top 10 multispecialty hospitals in India.
It is prominent for making use of high tech equipment and systems like IBM Watson technology for oncology patients.

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Manipal Hospital HAL Airport Road offers clinical expertise in over 60 specialties It is world renowned for its high-quality infrastructure and cutting-edge technology.
The medical experts at this hospital offer their skills to both national and international patients. It is the largest healthcare brand in India.
Manipal Hospital is ranked as the Best Hospital in Bangalore for the past 8 years by The Week Magazine.
Ranked among the top 5 hospitals in “INDIA’S MOST CARING HOSPITALS” survey.
The hospital Won the prestigious Golden Peacock National Quality Award 2005 in the Service category.
Manipal Hospital aims at providing supreme and affordable tertiary healthcare to all.

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Aster CMI Hospital Bangalore

Number of beds: 500
ICU Beds: 50
Airport Distance: 27 KMs

About Hospital:

Aster CMI hospital was established in 2014, from a single medical centre to a performance driven healthcare enterprise, spread across 320 establishments in 9 countries.
Aster CMI hospital is one of the top hospitals in Bangalore, with serene ambience, spacious interiors, advanced medical facilities.
Aster CMI is one of the best multispecialty hospitals in Bangalore as per the Times of India (TOI) All India Multispecialty Ranking Survey.

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It is the top super-specialty hospital in Bangalore with contemporary state-of-the-art facilities accommodating close to 500 beds.
Since its inception, Aster CMI has set a benchmark in terms of its world-class infrastructure, clinical excellence, the team of doctors available for numerous specialties under one roof.
Aster CMI Hospital has also been recognised as one of the top hospitals in India for Cardiology.

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Kokilaben Dhirubhai Ambani Hospital

Number of beds: 750
ICU Beds: 180
Airport Distance: 8 KMs

About Hospital:

Kokilaben Dhirubhai Ambani Hospital is a top-class multi-specialty tertiary care hospital with a capacity of 750 inpatient beds.
The hospital has a large number of ICU beds in Mumbai, with 180 ICU beds and 240 independent clinics,having the capacity to deal with over 9,000 outpatient consultations every day.
The hospital prides itself for having a Full Time Specialist System which ensures easy access and comprehensive use of resources to various specialists .

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They are the first in India to have a 3-room Intraoperative MRI Suite (IMRIS).
It is the fastest 1000 Robotic Surgeries within 48 months of Launch.
It has been awarded the smartest hospital building in India by Honeywell and the Times of India.
Kokilaben Dhirubhai Ambani Hospital has been ranked no. 1 in western India for Dermatology, Diabetology, Plastic/ Cosmetic Surgery and Trichology.

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We offers these Services

Providing a doctor’s opinion and proper quotation
Selecting the best hospital and doctor as per your case
Arranging a call with the doctor (if the case required)
Visa assistance, Providing Visa Invitation Letter (VIL)
Providing full guidance how to get Visa from your country
Providing total cost including treatment, air tickets, accommodation, and food
Assitance to book flight ticket from your country
Arranging airport pick up/ drop
Providing professional language interpreter
Booking accommodation and guest house as per your budget/ prefrence
Providing help in money exchanging
Providing local sim card
Arranging video consultation with specialist doctor if case requires

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